Clinical features and treatment of kidney disease FSGS

FSGS

FSGS kidney called the Focal segmental glomerulosclerosis, glomerular capillary loop refers to focal segmental sclerosis or hyaline degeneration, no significant cell proliferation of a class glomerular nephropathy.

A common type of FSGS kidney pathology are of primary nephrotic syndrome, 50% of patients with primary nephrotic syndrome pathological type FSGS nephropathy, renal biopsy can clear the disease. The disease mostly occurs in children and adolescents, more men than women, minority FSGS kidney patients before the onset of upper respiratory tract infection or a history of allergic reactions.

In addition, the occurrence of familial FSGS kidney disease may have a genetic predisposition, there atopy in the crowd relatively common kidney disease FSGS, the main clinical manifestations and features:

(1) The first clinical symptoms of nephrotic syndrome, microscopic hematuria is more common, and occasionally gross hematuria, about two-thirds of adult patients with mild persistent hypertension.

(2) Urine examination showed a small number of patients with kidney disease FSGS asymptomatic proteinuria. The vast majority of non-selective proteinuria, but early may have highly or moderately selective.

(3) blood test serum C3 levels were normal, decreased IgG levels.

(4) FSGS patients have kidney proximal tubular dysfunction performance, glomerular filtration rate and effective progressive decrease, upper respiratory tract infection or allergic allows a variety of symptoms.